When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...
Our lab studies the mechanism of eukaryotic chromosome replication. Chromosomes are the carriers of the genetic and epigenetic information and faithful chromosome replication is of fundamental ...
The research published in Nature on Dec. 25th, 2019, led by Dr. LI Guohong and Dr. ZHU Mingzhao from the Institute of Biophysics of the Chinese Academy of Sciences, has demonstrated that the histone ...
Mechanisms for replicating DNA / G.S. Brush and T.J. Kelly -- Origins of DNA replication / M.L. DePamphilis -- Roles of transcription factors in DNA replication / P.C. van der Vliet -- Roles of ...
Abd Wahab S and Remus D. Antagonistic control of DDK binding to licensed replication origins by Mcm2 and Rad53. eLife 2020; Jul 23;9:e58571. doi: 10.7554/eLife.58571. Meng X, Wei L, Devbhandari S, ...
BERKELEY, CA -The molecular machinery that starts the process by which a biological cell divides into two identical daughter cells apparently worked so well early on that evolution has conserved it ...
Nuclear-encoded regulatory proteins control mitochondrial translation. A few, however, are encoded by the mitochondrial DNA (mtDNA) and are produced by the mitochondrial translation machinery.